6dpIUI #1 and going crazy

I'm going crazy. Time is crawling...I'm only 6dpiui and I feel it has been weeks. And I feel nothing - an occasional cramp, but overall n-o-t-h-i-n-g. Yet I can't stop obsessing...  It's so hard not to get your hopes up and to keep it realistic.

Let us analogize to weather. If it says, "There is a 20% chance it will rain today,"  do you know what that means? I'm planning an outside BBQ or to go to the beach. That means NO rain is probably coming. Yet, when it comes to pregnancy, we hold on to the 20% chance like it is some huge number. Why is that?

I can't focus at work. I mean I'm still getting my hours in, but my work product is bound to suffer. I just want to know "yes" or "no" for sure. I'm 8dp trigger shot, so I may test in the morning to see if the hCg is all out of my system. I will let you know.

It would seem like such a waste to get a BFN when I had 4 mature follicles. If I can't get pregnant off that, then when can I?

Pet peeve of the day: People who say "I get pregnant when my husband just looks at me." Good for you.

3dpIUI #1

It just hit me as I was on my pregnancy bulletin boards that I'm on Cycle 19 of TTC. That is soooooooo depressing.

It does help, however, to have the ladies of http://www.pregnancy.org/ to help me through the tough times. Some of them have been trying for 3+ years (over 36 cycles) to be pregnant. Yet, they seem to stay optimistic and happy. They are my heroes!

As for me, I have no symptoms at all except cramping (which is totally expected on 3dpIUI and on Prometrium). I'm trying to stay positive, but I have a bad feeling about this month. A 20% chance is not much...

But that is OK...I have A LOT to look forward to in life. I going to be (and already am) a great attorney and I have a wondeful husband and friends. Additionally, I have the resources necessary to adopt if it comes to that which many do not. Yay! Look at the positives!

1dpIUI #1

I started the progesterone suppositories. Two words: Dear God. I pray none of you have to use those. And I have to do two a day for the next two weeks. Gross.

Due to the increased progesterone and the hcg shots, I'm a moody mess. One minute I'm happy as can be and the next I want to scream. Poor Ed - I hope this gets better over the next two weeks.

In other news, a friend of a friend was just diagnosed with a malignant brain tumor. She is 37 years old with three kids. Prayers and thoughts appreciated for this young lady during a devestating time.

Happy Fourth of July! As much of a struggle as this is, I am just thankful to be in the U.S of A. Imagine going through this elsewhere where there may not be the accessiblity to treatment that I have here or, I can't believe I am saying this, the health insurance that is covering EVERYTHING. I'm very thankful this weekend.

0dpiui #1

Well, today was the big day. I went in for IUI #1. It was really fast and painless - about 30 sec.

We had great news as well which has me more optimistic:

1) I did not ovulate yesterday. B\c the Ovidrel was causing the four mature follicles to grow even more, my ovaries are simply enlarged. Any cramping that I am feeling is the final "growth spurt" of the follicles. Plus, my sides and back were really cramping when I woke up this morning, so I think I am ovulating now. You were right, Amy! Thank you for calming me down!


2) Ed did his job superbly. We had 41 million sperm after the wash. Just FYI, the sperm go through a "wash" before an IUI. In a wash, the sperm is put through solutions to "weed out" the weakest sperm (bad motility, bad morphology). For an IUI, they want to see at least 2-3 million sperm, with average being 15-20 million. So, as you can see, Ed's 41 million was superb. They actually gave him a standing ovation. Although it does not necessarily improve our chances, it does mean that there are more sperm that can hopefully meet at least one of the four eggs.

3) Remember how I spoke about the high miscarriage rate in PCOS people? And remember how I said that in PCOS one of the main symptoms is obesity? Well, the P.A. said that the high miscarriage is usually attributed to the obesity factor. As such, she said that my chances of miscarriage are closer to that of a "normal" person - so only 15%. Yay!! That made me feel better too!

Illustration of IUI

So all-in-all it was a great appointment. I'm working from home today - with my legs in the air. Now begins the worst part of this process - the 2ww. And b\c I'm on HCG shots anyway, I have all the symptoms of pregnancy. It's going to be a long 2 weeks. Beta test is scheduled for July 14 @ 7:30 am. Ahhh...

16.5 hours until IUI

So I'm ready to cry. I have been "crampy" all day. Normally for me that is a sign of ovulation (at least when I've been on Clomid). When I was in a conference today, I was really crampy. Now, I feel just slightly crampy.  I'm so scared that it is happening tooo early (or already has happened) and I will have missed it by tomorrow morning at 11:00 am.

And, yes, I know the trigger shot is supposed to make me ovulate, but not before tomorrow morning after 11:00 am. I tried to call the doctor after my conference, but of course they closed at 4:00. I don't want to call the on-call doctor for something so minor.

Please just pray that it is a side effect of the Ovidrel (i.e., preparing me for ovulation) and not ovulation quite yet. I will be pretty devastated if I have four "very good" follicles and missed it b\c of timing. Unfortunately, you're not allowed to have sex for 48 hours before the IUI.

Off to an O's game. Keep us in your thoughts and\or prayers.

Trigger Shot

Here is the trigger shot:

I just gave the shot to myself (hopefully in the right area). Side effects include headache, nausea and vomiting, and fatigue. I'll let you know how it goes.

IUI #1 - Day 14

I have the doctor worried. I have 4 mature follicles ready to go. Today's measurement:

Follicle 1 - 20 mm
Follicle 2 -  18 mm
Follicle 3 - 18 mm
Follicle 4 - 17 mm

It looks like they all caught up to each other. So today he gave me a sheet on "the risk of having multiples." At the end though, being the lawyer that I am, I had him conceding that the chances of four are actually low. He essentially gave me these %:

Chance of pregnancy - ~15-20% [a little lower than normal]

If pregnant:
Chance of Twins - ~50%
Chance of Triplets - 20-30%
Chance of Quads - 15-10%

So just got the call. I take the trigger shot tonight. And IUI #1 occurs on 11:00 am Thursday morning. Unfortunately, my RE is out of town the next 2 weeks. I will have a stranger (I think a P.A.) doing the actual insemination. I'm kind of bummed about that, but I do trust all doctors at Shady Grove. Everyone is so nice and supportive there. We have a mini-celebration everytime we see a follicle grow. Plus, I've met the P.A. and she is really wonderful.

I start progesterone supplements 2 x a day on Friday. Then July 14th I go in for my BETA test to see if it worked.

My main emotions right now are excitement and hope. Unfortunately, ones chances are quite low even with IUI. Therefore, I'm likely just setting myself up for failure YET AGAIN. It's hard not to get excited, but the fall is so much harder when you are on a high. I have to keep my emotions on track and my mind off of it. So keep your fingers crossed.

IUI #1 - Day 13

The follicles continue to grow! Today's numbers:

Follicle 1: 16.8
Follicle 2:  15.6
Follicle 3: 15.2
Follicle 4: 14.8

About 1.8 cm in growth as expected. It does look as though Follicle 4 is dropping off, however, which is not necessarily a bad thing (based on the following).

Estrogen 594
LH 12.7
Progesterone .6

My estrogen level is once again indicating that three follicles have the potential to become mature eggs (~ a "dominant" egg puts out an estrogen level of 150-200). My LH went down which indicates, in conjunction with the progesterone level, that I have not yet ovulated, nor will I likely do so imminently. Dr. M says its probably "just where it wants to be right now." As such, when I surge it will likely near 40. This is a great thing at this point in my cycle!

On a "I got excited, but probably should not get my hopes up" note, Dr. M gave me a talk about the three follicles that are still in the race. He says that it looks as though all three may go to maturity, especially when given the trigger shots. If so, that means I have a greatly increased chance of multiples, especially in an IUI setting. I told him that ideally I would love to have three now and be done. He just shook his head and looked at me like I was crazy...haha!

I go back in tomorrow to see where were are. As we near closer to 20 mm, I will take the trigger shot and then the IUI will occur 36 hours later. I'll update tomorrow!

IUI #1 - Day 12

This is our first clomid\injections intrauterine insemination (IUI) cycle (note: different from IVF).

On cycle day 5-9, they had me take the usual 50 mg of Clomid. Most women seem to have side effects, but thankfully I never do. In fact, I think it makes me happier. It could be that psychologically I start to get hopeful that this month is "the month."

Day 12 was yesterday which means only one thing:  daily monitoring begins! I am to get an ultrasound every morning at 7:30 am until it is determined whether or not I will ovluate and, if so, when.

Day 12's ultrasound\blood work came back as a mixed bag! I had 3-4 eggs that looked as though they were going to win the "race to maturity." On a good note, this means the Clomid is working this round. On another good note, my estrogen numbers indicate that at least three of the follicles may release.The numbers looked like this:

1 follicle - 15 mm
1 follicle - 14.8 mm
1 follicle - 13.9 mm
1 follicle - 12.7 mm

Estrogen - 480
LH - 15.6

On the potentially not so good note, Dr. McClamrock does not know now why my LH is so high at this point. On day 12, it should still be around 2-5. Such a high number usually indicates that ovulation is 24-36 hours away, but my follicles are not big enough yet to be considered "mature." With Clomid, they want to follicles to be 19-21 cm before they begin injections to induce ovulation. Since follicles grow 1-2 cm a day, I should still be realistically 4 days away from ovulating. The only thing to do is to wait until I get Day 13 blood work back to see which way the LH surge is going. Because of this uncertainty, we are holding back on the hormone injections until we know for sure.

The call for today's bloodwork should come at about 3:00 pm.

Pet Peeve of the Day:  Women with PCOS should get discounts on pregnancy tests because we have to take so many. We have to take them at least 4 times before they will give us Provera to start the next cycle. Then you take 100000 during the time that should be the "end." I have spent probably $400 on pregnancy tests (including dollar store tests).